Irregular Webcomic is to me what coffee is to other people. It perks me up, I have it every morning.
Irregular Webcomic is a collection of about five or so storylines (though more occur, there's about five active), and it is a wonderful LEGO and Photoshop blend that will spruce up your day. It's on the PG intellectual side. It shirks politics, but still makes plenty of nerd humor and puns. It's hobbit forming, I'll give it that (an example pun). It has science fiction, fantasy, Indiana Jones and Mythbusters character parodies, as well as Death, in his million trillion forms.
Recommended for all ages, but generally an intellectual crowd will enjoy it more.
You'll probably learn something if you don't have multiple college degrees, and you'll enjoy it no matter what.